A new quinoline sensitizer-centered lanthanide chelate and its use for protein labling on Ni-NTA beads for TR LRET assays.

نویسندگان

  • Sung Hoon Kim
  • Pinghua Ge
  • John A Katzenellenbogen
چکیده

A quinoline sensitizer-centered lanthanide chelate system of novel design for TR-LRET was prepared; it exhibited high labelling efficiency with a his-tagged protein (ERalpha-LBD) on the Ni-NTA beads, using a mixed metal chelate protocol, and it functioned well in TR-LRET protein-protein interaction assays.

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عنوان ژورنال:
  • Chemical communications

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2009